Research Projects Funded

2011 HHT Research Priorities

A committee composed of HHT researchers and clinicians have identified particular areas of research that the HHT Foundation should focus its' efforts on achieving and have determined how the Foundation agenda can be promoted to NIH and beyond.

Read the Research Committee Report

RESEARCH PROJECTS FUNDED

• 2011
• 2008
• 2007
• 2006
• 2005
• 2004

---------------------------------------------------------------------------------------------

HHT FOUNDATION INTERNATIONAL RESEARCH PROJECTS FUNDED

The HHT Foundation International is supportive in funding research in understanding the mechanism of HHT disease, novel therapeutic approaches to treatment and management, and translational research. The HHT Foundation uses specific criteria in evaluating proposals for funding.

HHT FOUNDATION INTERNATIONAL GRANT REVIEW CRITERIA

Significance: Does this study address an important problem? If the aims of the application are achieved, will scientific knowledge or clinical practice in HHT be advanced? What will be the effect of this study on the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?

Approach: Are the conceptual or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics?

Innovation: Is the project original and innovative? For example: Does the project expand and/or challenge existing paradigms or current clinical practice; does it address an innovative hypothesis or critical barrier to progress in the field? Does the project develop or employ concepts, approaches, methodologies, tools, or technologies that are novel for this area?

Investigators: Do the investigators have appropriate training and expertise to accomplish this work? Is the work proposed appropriate to the experience level of the principal investigator and other researchers? Does the investigative team (if applicable) bring complementary and integrated expertise to the project?

Environment: Does the scientific environment in which the work will be done contribute to its probability of success? Does the proposed study benefit from unique features of the scientific environment, or subject populations, or employ useful collaborative arrangements? Is there evidence of institutional support?

Need: Importance of this funding to this research. Is funding from the HHT Foundation International crucial to the success of this research, or merely helpful?

OVERALL EVALUATION: Please record a score reflecting the overall impact of the project on the field, weighting the review criteria above as you feel appropriate for each application. An application does not need to be strong in all categories to be judged likely to have a major scientific impact and, thus, deserve a high rating. For example, an investigator may propose important work that by its nature is not innovative, but is essential to move HHT research forward, or improve clinical decisions or outcomes. Please score each application from 0 to 100, with 100 representing a perfect application, and 0 a worthless one.